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Up at 5AM: The 5AM Solutions Blog

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Complete DNA Sequencing for the Domestic Cat? Done!

  
  
  
  
336px Gustav chocolate

An international team of researchers announced this month that they have sequenced the entire genome of the domestic cat. Specifically, they have sequenced the genome of Cinnamon, a female Abyssinian cat from the University of Missouri. Because there are roughly 250 diseases that cats and humans have in common, the research has implications for improving human health, as well as the the health of the internet's favorite furry friend. 

Liquid Biopsy - Curing Cancer from the Inside Out, Ctd.

  
  
  
  
bloodtestkit

Last week, we did a post on curing cancer at the gene-level.  But what about using genes to diagnose cancer? A feature story in the MIT Technology Review looks at research happening at Johns Hopkins University on that very possibility.

Newborn Screening is Personal

  
  
  
  
babyfeet

It's no secret that we human beings will go to great lengths to keep our families safe and healthy. In the late 1940s, Dr. Robert Guthrie, a cancer doctor, learned that his son, John had mental retardation. About a decade later, after switching his focus to finding the causes of mental retardation, Dr. Guthrie's niece was born with phenylketonuria (PKU), a genetic disorder that prevents the body from metabolizing the amino acid phenylalanine. Untreated, PKU can lead to mental retardation. 

Curing Cancer from the Inside Out

  
  
  
  
livestronghands

Over the past year, The Atlantic magazine has published several articles on curing cancer. Overall, the tone in each article is hopeful, but balanced.

Deleting HIV

  
  
  
  
DeleteKey

The numbers are daunting:

Map of Biomedicine: Premarket Approval for Diagnostic Products

  
  
  
  
MoB Information Architecture Companion Dx Hilite

In the last few Map of Biomedicine blog posts I’ve talked about several different ways that diagnostic products can get to market. Laboratory-developed Tests (LDTs) and tests that get 510(k) approval (for tests that are similar to existing tests) are two ways.

Skin Cancer - Tales from Two Hemispheres

  
  
  
  
sidtheseagull

Experts around the globe agree that most skin cancers are preventable. They disagree, however, on what skin cancer prevention looks like.

Long Commute? Update Your Software.

  
  
  
  
5AMers think about software a lot.

5AMers think about software. A lot.

Practicing Our Craft - Developing Great Software

  
  
  
  
craftsmanship s

The clock shows a minute past noon. The stragglers of a steady stream of 5AMers finish sneaking in the conference room door and quickly take their seats. Someone dims the lights while another finishes pulling the shades. A hush comes over the room. “Everybody ready?” Nods answer. A mouse cursor clicks the play button. The frozen bespectacled figure on the projector screen comes to life. In a stern voice, he declares, “Integrated tests are a scam – a self-replicating virus that invades your projects! It threatens to destroy your codebase, to destroy your sanity, to destroy your life.” Another 5AM Tech Talk begins…

FDA: "Get More Men in Breast Cancer Trials"

  
  
  
  
HIS

This year, 2000 men in the U.S. will be diagnosed with breast cancer. Fewer than 500 of them will die from the disease. In general, men's chances of developing the disease are about 100 time less that of women's. Comparatively, about 200,000 women will receive a breast cancer diagnosis.

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